Neither renal composite 1 (40% eGFR decline, RRT, or renal death) nor composite 2 (composite 1 variables plus macroalbuminuria) was reduced by exenatide in unadjusted analyses
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In a response (PDF) issued on April 15, plaintiffs argued that discovery will reveal how much the manufacturers, Eli Lilly and Novo Nordisk, knew about the risks of GLP-1 RA gastroparesis risks, demonstrating that they intentionally downplayed those risks to patients and the medical community
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The growing prevalence of metabolic syndrome has only exacerbated these challenges as our transplant recipients either have pre-existing diabetes mellitus and/or mild CKD or develop these conditions post-transplantation
However, compounded medications do not undergo the same rigorous testing by the FDA