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The includes direct messaging for non-emergency questions and clear guidance on when to seek urgent care

As you can see, this is a downward spiral

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As the HPT axis has long been involved in the research of depression (106), it is reasonable to believe that the dysfunction of the HPT axis in GD, with its effect of disrupting neurotransmitter metabolism, inducing oxidative stress, contributing to other complications and so forth, has a potentially vital effect on the development of depression