Ideal for adults with a BMI of 30 or higher, or 27 with an additional weight-related condition, this once-weekly injection has proven to help users lose around 15% of their body weight over a 68-week period
Across both diabetic and nondiabetic cohorts, GLP-1s were associated with a meaningfully lower fracture risk
Start slowly to avoid worsening bloating or fullness
Vegans and vegetarians may not get enough vitamin B12 because it is mostly found in animal foods
Unlike some diabetes medications such as thiazolidinediones, tirzepatide's mechanism of action does not directly promote fluid accumulation, and clinical trials have not identified edema as a common adverse reaction
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