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1 mM Metformin and Its Combinations with 10 nM Semaglutide and 10 nM Tirzepatide Exhibit Enhanced Modulatory Effects on HG-HL-Induced Apoptosis and Apoptotic Biomarkers All three medications at the defined doses used in this experiment, as well as the combinations of 1 mM metformin with both 10 nM semaglutide and 10 nM tirzepatide, mitigate HG-HL-induced apoptosis in INS-1 -cells (Figure 1A)

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