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Viral and cellular determinants of hepatitis C virus RNA replication in cell culture

Limitations and research gaps: Because this work is a synthesis of available studies, conclusions are constrained by limitations in the underlying literature, most notably variability in inoculation/phenotyping protocols, uneven multi-location validation, limited functional validation of candidate genes in sesame, and incomplete characterization of pathogen diversity and genotype environment interactions (especially drought)

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During liver fibrosis, the 2-AR expression also increases markedly

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