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Bleecker*, Deborah Meyers, Wendy Moore, Stephen Peters, Rodolfo M

Notably, increased expression of the transcription factor MYC, which is strongly associated with glutamine metabolism, induces the expression of several key enzymes in nucleotide biosynthesis, including phosphoribosyl pyrophosphate amidotransferase (PPAT) 36

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Sources: Weschawalit, S., Thongthip, S., Phutrakool, P., & Asawanonda, P

Vitamin D and probiotic cosupplementation affects mental health, hormonal, inflammatory and oxidative stress parameters in women with polycystic ovary syndrome

Nevertheless, future translational studies must focus on developing drugs with high tissue specificity and isoform-selective activity to account for the metabolic duality inherent to lactate biology