Activation of a receptor by its endogenous agonist may activate G protein- and -arrestin-mediated signaling, phosphorylation of the receptor by one or more protein kinases, desensitization, and receptor internalization, which is then followed by either recycling or degradation of the receptor
This makes it a highly targeted tool for metabolic research
Injectable peptides after reconstitution typically require refrigeration
Advances in experimental medicine and biology, 264, 7984
SIRT1 activation also promotes fatty acid oxidation, reduces lipogenesis, improves insulin sensitivity, and enhances cellular stress resistance
Outer thigh (vastus lateralis) Great for self-injecting because its easy to reach and safe