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Of the six studies that measured co-factors of the -glutamyl cycle or trans-sulphuration pathway, five studies showed elevated levels of vitamin B6 in children with autistic disorder or autism spectrum disorders compared to controls [73, 76, 87, 92, 93], one showed a decrease in erythrocyte selenium in children with autistic disorder [78] and another showed no change in whole blood selenium in children with an autism spectrum disorder compared to controls [87]

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