(2023, The Lancet) Type 2 Diabetes Trial Study Design: Randomized, double-blind, placebo- and active-controlled Phase 2 trial in adults with type 2 diabetes
L-carnitine, an amino acid derivative, is known for its role in energy metabolism, specifically in transporting fatty acids into the mitochondria to be burned for energy
In Phase 2 clinical trials, retatrutide was administered as a once-weekly subcutaneous injection using a structured dose-escalation schedule to improve gastrointestinal tolerability
Retatrutide is being studied as a triple hormone-receptor agonist
Nature 171 , 737738 (1953)
Dilated cardiomyopathy typically presents with heart failure symptoms, while restrictive cardiomyopathy is rarer and often associated with systemic diseases