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When co-treated with Fer1, the PI uptake was effectively suppressed in the RSL3-treated 3D PTC spheroids, further reinforcing our previous findings of cytoprotective effects and ferroptosis pathway abrogation by Fer1 in RSL3-treated PTC cells in 2D

This observation could encourage investigation into whether this treatment is able to induce additional benefit

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Hyperchromatism is sometimes a feature

They also stated: "Finally, we have not examined dogs with left-heart disease

Funding This study was partially supported by Fundao Carlos Chagas Filho de Amparo Pesquisa do Estado do Rio de Janeiro (FAPERJ - E-26/201.289/2022), Brazil