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A brainkidney connection: the delicate interplay of brain and kidney physiology

Tabernor J, Grothey A, Van Cutsem E, Yaeger R, Harpreet W, Yoshino T, Desai J, Ciardiello F, Loupakis F, Hong YS, Steeghs N, Guren T, Arkenau H, Garcia-Alfonsi P, Elez E, Gollerkeri A, Maharry K, Christy-Bittel J, S|| K

His glycaemic control remained stable with an HbA1c of 5.8%

However, in a mouse model of diabetes, intravenous administration of metformin does lead to accumulation of metformin in the enterocytesmost notably in the small intestine [12]

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