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[6] SAM may act as a methyl donor in the metabolic processes that control lipid homeostasis, DNA stability, gene expression, and neurotransmitter release, which may account for the benefits it confers
Iron is also found in the brain, providing conditions conductive to ferroptosis in Wilson disease
Global, regional and national burden of osteoarthritis 1990-2017: A systematic analysis of the global burden of disease study 2017
Collectively, these studies indicate that modulation of NAD + levels affects additional critical cellular pathways other than mitochondrial homeostasis
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