Patients with Normal Intestinal Absorption: Where the oral route is not deemed adequate, initial treatment similar to that for patients with pernicious anemia may be indicated depending on the severity of the deficiency
As you say you've " tried oral B12, which made no difference " it may well be that you have an absorption problem and will need injections
At week 208, mean weight loss in the semaglutide group analyzed as first on-treatment was 11.7% compared with 1.5% for the placebo group (Fig
Patients have been "tanked up" with daily injections, followed by weekly and then periodic ones that may continue the rest of their lives
When intrinsic factor is lacking, oral B12 may not be absorbed effectively
As research continues to reveal new applications and mechanistic insights, this compound stands poised to contribute to breakthrough discoveries across the expanding landscape of metabolic biology and translational research