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86 Overall, the evidence is overwhelmingly in favour of the use of methyl-B12, alone or alongside other treatments, in diabetic neuropathy, with oral and injectable B12 showing benefits

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formulated BDNF(brain-derived neurotrophic factor)-quercetin alginate nanogels and delivered them intranasally, resulting in a nearly 50-fold enhancement in the bioavailability of quercetin compared to oral treatment (269)

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