Symptoms that may indicate low Vitamin B levels include fatigue, depression, low blood pressure, constipation, memory loss, weakness, sore tongue, tingling and numbness in fingers and toes, mood changes and difficulty walking
doi:10.1056/NEJM198806303182604
Wang, S
Maintenance doses are typically 1 mg every 2-3 months for life High-dose oral therapy (1000-2000 micrograms daily) may be effective in selected patients with pernicious anaemia under clinical supervision, as passive diffusion can compensate for absent intrinsic factor, though this is not routine first-line treatment in the UK The water-soluble nature of B12 means that high-dose supplementation carries minimal risk of toxicity , making it a safe option for individuals with confirmed or suspected deficiency
[5] Pantothenic acid (vitamin B, provided as dexpanthenol) is a building block of coenzyme A, a critical coenzyme in the Krebs cycle and fatty acid oxidation
The result is a reduction in infections and the use of sterile injections
