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They work through entirely different mechanismsnaproxen inhibits COX enzymes to reduce inflammation and pain, whilst semaglutide acts on GLP-1 receptors to regulate appetite and glucose metabolism

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Thus, GLP-1R agonists show encouraging potential as stroke-protective agents, but there is still a need to investigate their effects in further clinical therapeutic trials

Consideration of alternative diabetes treatments if a temporal relationship between Ozempic and mood changes is suspected