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Pharmaceutics 15:452 Bojarska J, Mieczkowski A, Ziora ZM, Skwarczynski M, Toth I, Shalash AO, Parang K, El-Mowafi SA, Mohammed EH et al (2021) Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold

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BPC-157's sequence does not contain cysteine (which is the most oxidation-prone residue), but other residues can still degrade under prolonged air and light exposure

Especially when the alternative carries side effects that push plenty of users to quit