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Extracellular glutathione S-transferase omega-1, a cytosolic enzyme that modulates the S-thiolation status of intracellular factors involved in the inflammatory response, and its polymorphisms have been associated with an increased risk to develop COPD and could have a biological and clinical significance in cystic fibrosis (115)

doi: 10.1186/s10194-016-0606-0

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Our PRE experiments suggest that hydrophobic interactions play a crucial role in the interaction between FOXO4 FHD and p53 TAD