i am not losing weight on semaglutide Why Semaglutide? 12 Reasons You're Not Losing

Several factors may contribute to this change

The most commonly reported effects are mild headache, light water retention, mild appetite increase, and tingling in the hands or feet

Its active for about two to three minutes, so you have a temporary feeling of fullness

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Genetic variations What complicates things a little more is that some people have a genetic variation (methylenetetrahydrofolate ( MTHFR) C677T SNP) which inhibits the way the body processes folic acid and other important B vitamins