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We have previously shown this Bcl-2 inhibitor to induce GSH-sensitive mitochondrial oxidative stress and intrinsic apoptosis in CGNs [37, 38]

2.14 Animal model and experimental protocol 2.14.1 Establishment of ischemia-reperfusion mouse model and drug administration protocol Mice (C57BL/6 strain) were housed under controlled environmental conditions with a 12-hour light/dark cycle and ad libitum access to standard rodent chow and water

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The combination of phentermine and semaglutide is not FDA-approved, and there is limited clinical research specifically evaluating the safety and efficacy of using these medications together

doi: 10.1515/jpem-2022-0074 65 ButlerMGGargU

But ALCAR's benefits extend beyond the brain, influencing energy metabolism and potentially supporting cardiovascular health