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Future research should focus on elucidating the precise molecular pathways involved in oxidative stress and exploring novel antioxidant therapies that could restore balance to the redox environment within the testes, ultimately enhancing fertility outcomes in affected individuals ( 2.3 Destruction of the blood-testis barrier and induction of autoimmune responses The blood-testis barrier (BTB) serves as a critical protective structure that maintains the immunological privilege of the testicular environment, allowing for the development of germ cells without interference from the immune system ( Moreover, the breakdown of the BTB is not merely a localized phenomenon

The article does not name the trials behind that figure, and its own table gives twelve-week ranges that look unusually high, so the numbers are best treated as illustrative