Metformin analogues Metformin is the most used drug in the treatment of type II diabetes in the world
doi: 10.4269/ajtmh.16-0434 139 FrasierKMGallagher-PoehlsCCochraneMRoyD
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2024;385: e078242
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This situation would lead to a self-perpetuating cycle, in which the free radicals generated would induce GSH depletion, thus increasing oxidative stress that would reduce antioxidant enzyme levels, which would further reduce GSH synthesis