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Clinical trials have reported gallstones in 1.5% of patients on a 0.5 mg dose and 0.4% on a 1 mg dose, compared to 0% in the placebo group

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Taking these medications together means starting both at lower doses and titrating slowly to minimize overlapping digestive symptoms

Omega-3 Fatty Acids (DHA/EPA) Why It Works: Omega-3 fatty acids, particularly DHA, are critical components of sperm cell membranes

This accessibility allows patients to sustain treatment long-term while implementing lifestyle strategies that maximize both fat loss and skin health outcomes

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