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These findings demonstrate that lactoferrin-PLGA nanoparticles enhanced the brain delivery of CAY10603, improving mitochondrial function and limiting the oxidative stress and -synuclein aggregation 20

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From evaluating therapeutic response in relevant in vivo models to helping researchers better understand inflammatory mechanisms, collaborative preclinical research plays an important role in moving potential therapies closer to patients

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Results Interaction of glutathione with hematin When glutathione (5 mM) was mixed with hematin (20 M) in phosphate buffer (10 mM, pH 8.0) containing potassium chloride (20 mM), a shift in the peak absorbance from 618 to 655 nm was observed (Fig