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In addition to the G q/11 pathway, the G i/o pathway has also been shown to be recruited by the ghrelin receptor

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Hepatic fat accumulation results from an imbalance between lipid acquisition and lipid disposal, which are regulated through four major pathways: uptake of circulating lipids, de novo lipogenesis (DNL), fatty acid oxidation (FAO), and export of lipids in very low-density lipoproteins (VLDL) (Fig

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