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Its very hard to fight biologyand we have to change how we think about that.

Furthermore, the reduced glucagon levels can lead to a decrease in food intake and an increase in energy expenditure, resulting in a favorable shift toward weight loss

doi: 10.1155/2016/8917578 36 ShinSJChungSKimSJLeeEMYooYHKimJWet al

NTS neurons that express preproglucagon (Ppg) (and that produce the food intakesuppressing PPG cleavage product glucagon-like peptide-1 [GLP1]) represent a subpopulation of mouse LepRbNTS cells

Front Cell Infect Microbiol 2021;11:595575.ArticlePubMedPMC 97

Throwing Up on a GLP-1: Causes, Management and When to Seek Help Throwing up on a GLP-1 medication is a recognised side effect that affects a notable proportion of patients using these treatments for type 2 diabetes or weight management