These structures occupy a uniquely powerful position in biology: they are too small to be classified as full proteins, yet too biologically active to be dismissed as simple building blocks
Its especially effective when inflammation is a barrier to recovery
When prolactin is evaluated by two-site immunometric assays, large amounts of prolactin saturate both the capture and the signal antibodies, impairing their binding, causing serum prolactin to be underestimated (the so-called high-dose hook effect)
It binds to GHRH receptors on anterior pituitary somatotrophs, stimulating synthesis and pulsatile secretion of endogenous growth hormone
These phenomena may reflect the immunosuppressive effects of pregnancy
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