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95% CI 0.93, 1.01), MACE (HR 0.95

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Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS

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One key challenge is that these biologics typically require injection, which can limit patient compliance and convenience

The addition of high dose niacin was intended to increase HDL ("good") cholesterol, reduce elevated triglycerides, and, most importantly, reduce the risk of heart attacks and stoke