[1] These medications work by mimicking the action of naturally occurring GLP-1, an incretin hormone that stimulates insulin secretion in response to food intake, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways
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Yang J, Yin J, Gao H, et al
Figure 23: Photograph of Professor Graeme Bell in San Francisco taken by Mitsuko Seino in the parking lot of Chiron Corporation, 1984, credit: Accili, Bell
Water for Injection: Used in a quantity sufficient to make up the volume
Since its US FDA approval in June 2021 and subsequent EU and Japan approval in 2022 and 2023, respectively, for chronic weight management, WEGOVY has rapidly gained traction