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The 28.7% average weight loss observed in TRIUMPH 4 places this medication in a category of its own, which should strengthen the case for expedited review

It can have both short-term and long-term effects on the body

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GSH and zinc have a complicated relationship that affects genomic integrity through direct antioxidant actions, DNA repair mechanism regulation, and gene expression modulation [75]

Additionally, when many patients dropped out of the trials because the GLP-1 receptor agonists didnt work or the side effects were too bad, that data should have been counted

doi: 10.2337/diabetes.54.2.482 37 LiYHansotiaTYustaBRisFHalbanPADruckerDJ