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Curr Nutr Rep 14 , 63 (2025)

The Role of Healthy Volunteers in First-in-Human Studies One of the most significant contributions of healthy volunteers is in first-in-human (FIH) studies

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The injection is subcutaneous, meaning just under the skin, done with a very fine needle into the abdomen, thigh, or upper arm

Osmotic pumps filled with PBS were used as controls

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