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Cys151 residue is required to inhibit Keap1-mediated Nrf2 degradation, thus itaconate upregulates Nrf2 levels via Keap1 alkylation ( Figure 3 )
Study background and details: The study included health data for 7,044 adults admitted to a hospital for acute ischemic stroke between January 2000 and June 2022 in the Rochester Epidemiology Project
27 Renaud S, Ciavatti M, PERROT L, Berthezene F, Dargent D, Condamin P
10.15547/bjvm.2020-0091 [Online ahead of print]
The resulting clone, LaccID, was deployed for both EM and cell surface proteome mapping in mammalian cells (Fig
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