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More than weight loss, the drug has demonstrated ancillary advantages, including up to an 80% reduction in liver fat and alleviation of chronic knee pain and sleep apnea

The most frequent TEAE was decreased appetite ( n = 5)

E., Mahecha G., Marques R

Neurons responsiveness to hunger and satiety signals (as ghrelin, cholecystokinin, and PYY) are also modulated by body energy stores (represented by leptin and insulin).3 The aim of this article is to review the role of gut hormones as mediators of feeding behavior and of the different nutrients in modulating gut hormones production