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10.1371/journal.pone.0247076 100 LiZ.LiuY.ZhouT.CaoL.CaiY.WangY.et al (2022)
Fortunately, you cannot overdose on vitamin B12, as it is water-soluble, so adding more is not harmful
It is most effective when used alongside professional periodontal scaling and root planing, not as a standalone intervention