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Primary conclusions emphasized no significant average group differences in neurobehavioral outcomes, but secondary and re-analyses highlighted signals in subgroups, dose-response relationships, renal biomarkers, and genetic susceptibility.

This is compared to only 30% in the control group

however, severe nausea or vomiting requires dose adjustment or medical evaluation

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Stopping treatment abruptly allows hunger hormones to return to previous levels, making appetite increase again and significantly raising the likelihood of regaining lost weight

doi:10.1371/journal.pone.0162106