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Encouragingly, experiments show that antioxidant interventions in aged animals (including administering melatonin or vitamin E) can restore some amplitude to circadian rhythms and improve activity/rest pattern stability (Reiter et al., 2024)

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The threshold of differential expression was set at 1.5-fold change

Colchicine para-aminosalicylic acid and heavy alcohol intake for longer than 2 weeks may produce malabsorption of vitamin B12

In comparison to the docking conformation, the chelation site of CuB shifted from the ether oxygen to the hydroxymethyl group, with the hydroxyphenyl group forming a hydrogen bond with S356

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