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Notably, elevated ROS levels also play a pivotal role in non-parenchymal cell damage within the digestive system, as exemplified in PHG associated with cirrhosis [368, 369]

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These eigenvectors dictate the nature of the transformation of protein over the simulation time and eigenvalue determines the magnitude of transformation, thus the projection of trajectory with these first two or first three eigenvectors determined the collective protein movements [63,64,65]