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Subsequent studies found that melatonin inhibited inflammation and ferroptosis mainly by activating MT2 and IL-33 pathways, and FTH-KO significantly exacerbated the inflammatory response after TBI, and eliminated the anti-inflammatory effects of melatonin

Since ghrelin promotes gastrointestinal motility in addition to GH release, the prokinetic effect of a selective ghrelin mimetic is biologically plausible and consistent with the rodent data from Venkova et al., 2009

Xin H-W, Wu X-C, Li Q, et al

doi: 10.3390/ijms24010137 63 LagetJHobsonSMuyorKDurantonFCortijoIBartochowskiPet al