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The observed accumulation of GSH in Sp treated cells was probably due to reduced activity of -glutamyl transpeptidase (GGT), an enzyme responsible for glutathione catabolism 36

Autoimmunity Reviews , 8(8), 697701

Yamada, M

Similarly, the same mutation in rodents also causes increased ROS in Schwann cells and leads to death of primary Schwann cells in culture

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