While these findings are still in the early stages, they suggest DSIPs biological reach extends much further into general cellular stress responses than we first thought
doi: 10.1042/bst20160474 40
The committee members who voted yes generally believed the risks to be minimal, while those who voted no tended to worry about safety risks and effectiveness, and expressed concern that adding the peptide to the compounding list would create a false impression that it has been evaluated with the same rigorous standards as an FDA-approved drug
This remains an area of active investigation rather than settled science
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Compounding this issue, certain mycotoxins have been shown in animal models to suppress the production of Diamine Oxidase (DAO), the primary enzyme responsible for breaking down dietary histamine in the gut
