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In recent years, it has been found that incretin, the star drug of hypoglycemic and weight loss, is also involved in bone remodeling regulation, in which GIP can inhibit postprandial bone absorption, and GLP-1 also indirectly mediates acute and short-term inhibition of bone resorption through hyperphysiological concentrations of insulin [54]
Slow gastric emptying: It delays the rate at which the stomach empties its contents, leading to a more gradual absorption of glucose, which is beneficial for managing blood sugar levels in type 2 diabetes mellitus
The glutathione peroxidase pathway is further regulated by System Xc-, an amino acid antiporter consisting of a disulfide-linked heterodimer of xCT/SLC7A11 and SLC3A2/4F2hc/CD98, and is inhibited by the ferroptosis inducer erastin (4)
A sample size of 58 (29 per group) had 80% power to detect a 0.6% difference in HbA1c between groups
Community-reported plateau-breaking: split
