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The only double-blind non-randomized clinical trial conducted in the 1980s was the subject of a Cochrane Systematic Review, which found inconsistent results regarding its benefits for children and no evidence of effectiveness in adults

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10.1210/endo.133.1.8391428 [DOI] [PubMed] [Google Scholar] White, C

How tirzepatide works Tirzepatide, also known by the brand names Mounjaro and Zepbound, is an FDA-approved dual-action GLP-1/GIP receptor agonist made by Eli Lilly