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hippocampal CA3 synapse loss, suppressed neurogenesis and chronic-stress BDNF reduction

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A post-hoc analysis of major semaglutide trials confirmed no significant differences in depression or suicidal behavior compared to placebo

Encapsulation into nanoparticles To enhance the pharmacological properties of the metal complex and provide cancer selectivity, Ru(II)-OH was incorporated into a polymer backbone that could self-assemble into tumor-targeting nanoparticles

However, semaglutide's effects on lipid metabolism appear to continue beyond the weight loss effect, suggesting the medication provides additive cardiovascular protection