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Common semaglutide side effects include: Nausea Vomiting Diarrhea Constipation Loss of appetite These side effects are usually mild and tend to reduce as the body adjusts to the medication

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To examine whether the chemical conjugation of MK-801 to GLP-1 mitigates the adverse hyperthermic and hyperlocomotive effects of MK-801, mice were subjected to body temperature measurements and open-field behavioural tests after chronic and acute drug administration, respectively

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