identified 12 human gut bacterial genera able to convert LCA to 3-oxoLCA and isoLCA: Adlercreutzia, Bifidobacterium, Enter-ocloster, Clostridium, Collinsella, Eggerthella, Gordonibacter, Monoglobus, Peptoniphilus, Phocea, Raoultibacter, and Mediterraneibacter [26]
128 Although the antioxidant effect of UA might have therapeutic benefits, high plasma concentrations of UA have been associated with obesity, insulin resistance, and hyperuricemia
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In addition to natural antioxidants, synthetic antioxidants have been extensively used in medicinal and food industries
Finally, vasoactive substances produced by vascular endothelial cells are also important factors in the regulation of blood pressure
