NNMT catalyzes the methylation of nicotinamide (vitamin B3) using S-adenosylmethionine (SAM) as the methyl donor, producing 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine
Moreover, the results suggest that supplementation with vitamin B12 holds promise as a therapeutic approach for patients with VCD in the context of long COVID
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Untreated vitamin B12 deficiency can lead to various physical, neurological, and psychological issues
For example, those with high blood pressure, heart problems, skin conditions, blood disorders, gout and low potassium levels should use vitamin B12 with caution and may want to consider talking to a trusted health care practitioner before starting supplementation
Many clients report noticeable improvements in energy, mood, and clarity within hours of treatment