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Examples such as acetylation and succination highlight the established importance of metabolite modifications, with diverse roles ranging from chromatin regulation to immune effector responses 1,2,3,4

The D-isomer (Dextroamphetamine) is more potent than the L-isomer (Levoamphetamine)

In an effort to develop such a drug members of our laboratory synthesized a number of AngIV-based compounds possessing extended half-lives by utilizing reduced peptide bonds (CH2-NH2) between residues

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