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Loss of BCKDK function resulted in hypercatabolism of Leu, Ile and Val, leading to abnormally low levels of these BCAAs in serum and in the brain (100)

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[7] [29] From June 1992, when finasteride was approved, until February 1995, the FDA received reports of gynecomastia in 214 men (median age: 71 yrs)