Furthermore, topical application of retinoids on melasma lesions could potentially be associated with secondary hyperpigmentation as a result of drug-induced irritation (Pitowska et al., 2022)
Many substances being discussed have enthusiastic supporters as well as critics who point to limited human clinical data
However, some individuals may need to speak with their healthcare providers to ensure that symptoms are manageable or to adjust their dosage if diarrhea persists or becomes severe
doi: 10.7759/cureus.10097 40 LiuJHanPWuJGongJTianD
There are some limitations acknowledged to this study, including a relatively low sample size (owing to the rarity of IIH) and a short follow-up period, partially mitigated by the standardized data collection and thorough quality control applied within the VIIH
These senescent cell clearance research findings have significant implications for anti-aging intervention development, chemotherapy recovery support, and understanding how cellular senescence contributes to age-related tissue dysfunction and disease pathogenesis