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These groups can still be titrated after the amino acid is incorporated into a peptide or protein, but the pKa of the titratable group on the side chain is not necessarily the same in a protein as it is in a free amino acid

Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells

Neither study showed a significant increase in amylase (7% for both studies) or lipase (28% in the LEADER trial and 31% in the SCALE trial) values after starting liraglutide compared with placebo, and the positive predictive values of amylase and lipase for pancreatitis were less than 1%

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